Analytical Assay of Betamethasone Pharmaceutical Dosage Forms by Visible Spectrophotometry

Kumar, D. Ravi and Rambabu, C. (2021) Analytical Assay of Betamethasone Pharmaceutical Dosage Forms by Visible Spectrophotometry. In: New Innovations in Chemistry and Biochemistry Vol. 2. B P International, pp. 14-20. ISBN 978-93-91882-38-9

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Abstract

Two simple and reproducible methods have been developed and validated for the determination of betamethasone in pharmaceutical dosage forms by visible spectrophotometry. Method-1 is based on the formation of meisenheimer like sigma -complex by the m-dinitrobenzene with the mentioned drug in presence of alkaline medium to from a colored chromogen measured at 490nm. The Method-2 is based on reaction between MBTH and drug under study in presence of alkali to from a colored chromogen measured at 620 nm. The findings of the investigation were statistically evaluated and recovery studies supported the correctness of the proposed approaches. The methods were successfully applied to the determination of betamethasone in pharmaceutical formulations.

Item Type: Book Section
Subjects: Universal Eprints > Chemical Science
Depositing User: Managing Editor
Date Deposited: 25 Oct 2023 05:05
Last Modified: 25 Oct 2023 05:05
URI: http://journal.article2publish.com/id/eprint/2841

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