Efficacy of Voltaren Suppository in Adjunct with Peri- Prostatic Nerve Block with Lignocaine as Analgesia for Transrectal Ultrasound- Guided Biopsy of Prostate

Objectives: To evaluate the efficacy of suppository voltaren as an adjunct analgesia during transrectal ultrasound (TRUS) biopsy using numerical pain score.

Methods: A total of 48 patients who were subjected to TRUS biopsy of prostate were enrolled in this study. The patients were randomly divided into 2 groups equally. In group 1, the patients received the standard peri- prostatic nerve block (PPNB) consisting of 10ml of 1% lignocaine. In group 2, the patients received peri- prostatic nerve block consisting of 10ml 1% lignocaine and in addition of voltaren suppository 100mg which was administered 1 hour before the procedure. During procedure, the patients were assessed on their pain score using numerical pain score 0-10 during insertion of transrectal probe, administration of peri- prostatic nerve block, during biopsy and 1- hour post- biopsy.

Results: There was significant lower pain score in with regard to group 2 patients during probe insertion, PPNB administration and during biopsy. Pain score 1 hour post- procedure was not significant as the pain score in both groups were generally low.

Conclusions: We believe that by adding voltaren suppository 100mg 1 hour before the procedure would be an advantage for patients as this study had shown significant lower pain score throughout the procedure with no increase in morbidity.