Determining the Effect of Curry Leaves and Cucumber Fruit on Lipid Profile in Menopausal Women with Hyperlipidaemia

Background: Hyperlipidemia raises the likelihood of developing cardiovascular disease (CVD). Hyperlipidaemia refers to the increased levels of total cholesterol (TC) and triacyl glycerol (TAG) in blood. The goal of this study was to determine the effect of curry leaves powder and slicing cucumber fruit on hyperlipidemia in the menopausal women of rural communities.

Methods: Thirty menopausal healthy women from rural communities (45–65 years old) with mild hyperlipidemia were randomly assigned to two groups: the control group, which received no treatment, and the experimental group, which received cucumber (100-125 g) and curry leaves powder (5 g) once daily for 45 days. The demographic variables were gathered through the use of a questionnaire. Before and after the intervention, fasting blood samples were collected to determine total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and triacyl glycerol (TAG).

Results: In the curry leaves powder and cucumber treatment groups, TC, LDL-C, and TAG were considerably (p <0.05) reduced. Only the curry leaves powder treatment group's HDL-C level (46.1±9.2 mg/dl) was substantially (p <0.05) raised (average 12 percent). Although the control group had higher mean values of TC, LDL-C, and TAG, the difference was not statistically significant. The HDL-C level in the curry leaves treated group was statistically higher (p =0.09) when the efficacy of the test compounds at the tested doses was compared.

Conclusions: Curry leaves and cucumber were effective in increasing HDL-C and decreasing LDL-C and TAG levels in menopausal women with hyperlipidemia, indicating a potential neutraceutical role in CVD treatment.