Application of Nutritional Medicine as an Adjunct in the Clinical Management of Hypertension: A Case Study with a Mango Leaf Tea Formula

The applications of nutrient based therapy in the treatment of medical disorders has served the global populations for many centuries, where up to 70% of the disorders and illnesses reported are linked to a nutritional component in the etiology of their pathophysiologic sequela. A nutrient rich mango leaf-ginger combination was added to the pharmacologic regimen as a refreshing tea to improve the clinical management of chronic mid-grade hypertension (HTN) in an NIDDM patient with effective glycemic control. Measures of systolic and diastolic blood pressure (SBP and DBP respectively) were obtained for the 4 weeks of control monitoring when taking a multidrug pharmacologic treatment consisting of metoprolol succinate, losartan potassium, and amlodipine (MLA regimen) for 6 months or more, followed by 4 weeks of a mango-leaf+ginger tea (MGT) combination. Measures of systolic (SBP) and diastolic BP (DBP) were obtained 6-12 hours after the multidrug regimen and resulted in a 13% decrease in both SBP and DBP after one week, a 17% reduction in both parameters after two weeks, and a 30% reduction at weeks 3 and 4 of the MGT trial. These results indicate that the addition of the MGT natural product regimen when added to the MLA treatment was contributing to a normalization of BP and an amelioration of HTN when the MLA regimen alone was incompletely effective due to multi-drug resistance or other factors. While the definitive basis for the improvement in the management of HTN is unclear, the margin of evidence suggests that the inclusion of the nutritional constituents of the nutritional adjunct including readily absorbable, organically bound magnesium and other minerals as Magniferin® in addition to the broad spectrum of antioxidant compounds contained in the mango leaf-ginger combination contributed a pivotal role in the improvement of cardiovascular indices of HTN.