Kelechi, Madubuike and Uzoma, Asuzu (2015) Anti-inflammatory Activities of the Leaf Chloroform Extract of Palisota hirsuta. Journal of Advances in Medical and Pharmaceutical Sciences, 2 (2). pp. 57-63. ISSN 23941111
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Abstract
Objective: To investigate the anti-inflammatory activity of the chloroform leaf extract of Palisota hirsuta (CLEPH).
Methods: CLEPH was evaluated for anti-inflammatory activity using standard experimental models of inflammation namely: Croton oil-induced mouse ear edema, carrageenan-induced rat paw edema and cotton pellet granuloma test. The activities of the extract at different doses were compared to indomethacin, a standard anti-inflammatory drug.
Results: In all the experiments, the chloroform extract of P. hirsuta showed in a dose-dependent manner, anti-inflammatory effects which were significant (p˂0.05) and comparable to those of indomethacin.
Conclusion: The results showed that CLEPH possess significant anti-inflammatory activity. This supports its use as an anti-inflammatory recipe in folk medicine.
| Item Type: | Article |
|---|---|
| Subjects: | Universal Eprints > Medical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 12 Jun 2023 03:55 |
| Last Modified: | 14 Nov 2023 04:33 |
| URI: | http://journal.article2publish.com/id/eprint/2086 |
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